He will replace Glenn Kerkhof, who is stepping down on 31 October after six years in the post.
Kerkhof will then join Chiltern’s owner Czura Thornton as a new partner, and will join Chiltern’s board of directors.
Esinhart will become the CRO’s new chief executive from 1 November. He is currently Chiltern’s senior executive vice president of global scientific services, and has also served with the company for six years.
Esinhart has more than 24 years of industry experience and brings a track record of scientific excellence, operating performance and service delivery, according to Chiltern.