Bristol-Myers Squibb is to close one of its manufacturing facilities in Ireland with the loss of 130 jobs, while a further 30 posts will go at another site.

The US major issued a statement saying that changing market demand for a number of products manufactured at its Cruiserath facility in Blanchardstown near Dublin means the site will close by the end of 2015. B-MS' other Irish plant, in Swords, will continue operations, but one unit will cease manufacturing by the end of the next year, resulting in 30 jobs going.

The Swords facility, which employs some 320 people, will remain a key supplier of bulk pharmaceuticals, the company said.

Susan Hynes, general manager of API operations in Ireland, noted that the firm has "a long history" in the country "and the company’s presence here plays an important role in the B-MS global manufacturing network". It is working with IDA Ireland, the country's investment agency, "to explore potential future uses of the Cruiserath facility and will endeavour to minimise job losses in Ireland’.